Human cDNA probe detects RFLP on chromosome 12, OL 202 (HGM8 designated no. D12S9).

Human cDNA probe (OL167,D21S109) detects RFLP on chromosome 21.

RFLP detected at the 8924 locus by a thyroglobulin cDNA probe

SOURCE : 1660 bp corresponding to two contiguous Pst I fragments from human thyroglobulin gene cDNA cloned in pBR 322 (ref. I). This cDNA probe is located Ca 100 Kb 3 1 from PCHT 16/3.2-8.0 probe that reveals polymorphic fragments previously described by Baas et al. (ref.II). POLYMORPHISM : PvuII identifies a single two allele polymorphism Al : 13.2 Kb A2 : 4.4 Kb Mst II identifies a single two...

Testis-specific transcripts detected by a human Y-DNA-derived probe.

A genomic sequence (12f3), derived from the long arm of the human Y chromosome, detects a 1.6 kb mRNA, expressed in human and mouse testis, but not in other tissues tested by Northern blot analysis. Using 12f3 as a probe, a mouse cDNA, designated PL5, was isolated from an adult mouse testis cDNA library. The profile obtained by Southern blot analysis using PL5 as probe under high-stringency con...

StuI RFLP in the human ABL locus.

Source/Description: A 3.6 kb EcoRI fragment (lambda ABL3) containing portions of exons 7 and 8 and the intervening intron of the ABL oncogene was isolated from a chromosome 9-specific library (ATCC # LA09NS01) using a 1.7 kb Abelson murine leukemia virus probe (v-abl, ONCOR, Inc.). A single copy 1.8 kb BglII fragment (ABL3) was derived from the original lambda clone and detects the StuI RFLP. P...

An XmnI RFLP detected with a probe for the CYP2E gene locus on chromosome 10.

Source/Description: A 1.6 Kbp fragment of the cDNA clone for the human ethanol inducible cytochrome P450 gene cloned in pUC18 at the EcoRI restriction site (Song and Gonzalez, 1986). Polymorphism: Xmnl detects a two allele polymorphism with bands at 16 kb (Al), 11.4 and 4.6 kb (A2). Frequency: A total of 37 unrelated individuals of Caucasian origin were screened: Al 0.81; A2 0.19.